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Open Access Research article

Early malperfusion, ischemia reperfusion injury, and respiratory failure in acute complicated type B aortic dissection after thoracic endovascular repair

Jiang Xiong, Minhong Zhang, Wei Guo*, Xiaoping Liu, Tai Yin, Xin Jia, Hongpeng Zhang, Yongle Xu and Lijun Wang

Author Affiliations

Departments of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital, Beijing, China

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Journal of Cardiothoracic Surgery 2013, 8:17  doi:10.1186/1749-8090-8-17

Published: 23 January 2013

Abstract

Background

The aim of this study was to determine the early mortality and major complications of acute complicated type B aortic dissection (ACBD) after thoracic endovascular aortic repair (TEVAR).

Methods

Twenty-six consecutive patients with ACBD who underwent TEVAR were included. Clinical indications before TEVAR and in-hospital mortality and major complications after TEVAR were analyzed and compared with similar reports.

Results

TEVAR was technically successful in all cases. In-hospital mortality occurred in four patients (15%), and major complications occurred in an additional four patients (15%). Three of the four (75%) of the deaths were associated with malperfusion and ischemia reperfusion injury (IRI), and 3/4 (75%) of the major complications were caused by respiratory failure (RF).

Conclusions

In-hospital mortality associated strongly with severe end-organ malperfusion and IRI, while major complications associated with RF, during TEVAR. Our results indicate that malperfusion, IRI and respiratory failure during TEVAR should be carefully monitored and aggressively treated.